KLM flight KL 5378: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 07:00 Omaha (OMA) 10:19 Atlanta (ATL) S
KL 5378 Non-stop Airbus A320 (320) 2:19 Effective from 2026-10-25
Codeshare flight, operated by Delta Air Lines.(DL 1157)
Sat 11:10 Cancun (CUN) 3 14:49 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:39 Effective 2026-03-14 through 2026-03-28
Codeshare flight, operated by Delta Air Lines.(DL 1963)
Sat 12:15 Cancun (CUN) 3 14:55 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:40 Effective 2026-01-17 through 2026-03-07
Codeshare flight, operated by Delta Air Lines.(DL 1963)
Fri,Sun 12:17 Detroit (DTW) M 13:13 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:56 Effective 2026-03-29 through 2026-04-12
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Sat 12:25 Cancun (CUN) 3 15:11 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:46 Valid until 2026-01-03
Codeshare flight, operated by Delta Air Lines.(DL 1963)
Wed 12:42 Detroit (DTW) M 13:37 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A320 (320) 1:55 Effective 2026-04-01 through 2026-04-08
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Sat 12:42 Detroit (DTW) M 13:38 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A220-100 (221) 1:56 Effective 2026-04-04 through 2026-04-11
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Daily 12:47 Detroit (DTW) M 13:41 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:54 Effective 2026-04-13 through 2026-06-07
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Wed,Fri,Sun 12:47 Detroit (DTW) M 13:41 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:54 Effective 2026-06-10 through 2026-09-09
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Tue-Sun 12:47 Detroit (DTW) M 13:41 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:54 Effective 2026-09-10 through 2026-10-04
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Tue-Sun 12:47 Detroit (DTW) M 13:42 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:55 Effective 2026-10-06 through 2026-10-23
Codeshare flight, operated by Delta Air Lines.(DL 2697)
Mon-Fri,Sun 15:15 Cancun (CUN) 3 18:54 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:39 Effective 2026-03-08 through 2026-03-27
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Mon,Tue,Fri,Sun 16:30 Cancun (CUN) 3 19:14 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:44 Valid until 2026-01-04
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Wed,Thu 16:30 Cancun (CUN) 3 19:19 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:49 Valid until 2026-01-01
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Mon-Fri,Sun 16:40 Cancun (CUN) 3 19:25 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:45 Effective 2026-01-05 through 2026-02-11
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Mon-Fri,Sun 16:45 Cancun (CUN) 3 19:30 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:45 Effective 2026-02-12 through 2026-02-24
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Mon-Fri,Sun 16:45 Cancun (CUN) 3 19:30 Atlanta (ATL) I
KL 5378 Non-stop Airbus A321 (321) 2:45 Effective 2026-02-26 through 2026-03-06
Codeshare flight, operated by Delta Air Lines.(DL 1962)
Mon,Tue,Thu 18:20 Detroit (DTW) M 19:11 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:51 Effective 2026-06-08 through 2026-09-08
Codeshare flight, operated by Delta Air Lines.(DL 1842)
Sat 18:20 Detroit (DTW) M 19:19 Minneapolis/Saint Paul (MSP) 1
KL 5378 Non-stop Airbus A321 (321) 1:59 Operates only on 2026-10-24
Codeshare flight, operated by Delta Air Lines.(DL 1842)
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This flight number is listed as serving the following routes:


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KLM flight KL 5378: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
KLM KL5378
07:00
Omaha (OMA)

10:19
Atlanta (ATL) S
Effective from 2026-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1157)
Duration: 2:19, non-stop
Airbus A320 (320)
Direct Codeshare Flights:
KLM KL5378
11:10
Cancun (CUN) 3

14:49
Atlanta (ATL) I
Effective 2026-03-14 through 2026-03-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1963)
Duration: 2:39, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:15
Cancun (CUN) 3

14:55
Atlanta (ATL) I
Effective 2026-01-17 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1963)
Duration: 2:40, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:17
Detroit (DTW) M

13:13
Minneapolis/Saint Paul (MSP) 1
Effective 2026-03-29 through 2026-04-12
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:56, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:25
Cancun (CUN) 3

15:11
Atlanta (ATL) I
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1963)
Duration: 2:46, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:42
Detroit (DTW) M

13:37
Minneapolis/Saint Paul (MSP) 1
Effective 2026-04-01 through 2026-04-08
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:55, non-stop
Airbus A320 (320)
Direct Codeshare Flights:
KLM KL5378
12:42
Detroit (DTW) M

13:38
Minneapolis/Saint Paul (MSP) 1
Effective 2026-04-04 through 2026-04-11
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:56, non-stop
Airbus A220-100 (221)
Direct Codeshare Flights:
KLM KL5378
12:47
Detroit (DTW) M

13:41
Minneapolis/Saint Paul (MSP) 1
Effective 2026-04-13 through 2026-06-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:54, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:47
Detroit (DTW) M

13:41
Minneapolis/Saint Paul (MSP) 1
Effective 2026-06-10 through 2026-09-09
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:54, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:47
Detroit (DTW) M

13:41
Minneapolis/Saint Paul (MSP) 1
Effective 2026-09-10 through 2026-10-04
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:54, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
12:47
Detroit (DTW) M

13:42
Minneapolis/Saint Paul (MSP) 1
Effective 2026-10-06 through 2026-10-23
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2697)
Duration: 1:55, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
15:15
Cancun (CUN) 3

18:54
Atlanta (ATL) I
Effective 2026-03-08 through 2026-03-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:39, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
16:30
Cancun (CUN) 3

19:14
Atlanta (ATL) I
Valid until 2026-01-04
Mon
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:44, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
16:30
Cancun (CUN) 3

19:19
Atlanta (ATL) I
Valid until 2026-01-01
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:49, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
16:40
Cancun (CUN) 3

19:25
Atlanta (ATL) I
Effective 2026-01-05 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:45, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
16:45
Cancun (CUN) 3

19:30
Atlanta (ATL) I
Effective 2026-02-12 through 2026-02-24
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:45, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
16:45
Cancun (CUN) 3

19:30
Atlanta (ATL) I
Effective 2026-02-26 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1962)
Duration: 2:45, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
18:20
Detroit (DTW) M

19:11
Minneapolis/Saint Paul (MSP) 1
Effective 2026-06-08 through 2026-09-08
Mon
Tue
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1842)
Duration: 1:51, non-stop
Airbus A321 (321)
Direct Codeshare Flights:
KLM KL5378
18:20
Detroit (DTW) M

19:19
Minneapolis/Saint Paul (MSP) 1
Operates only on 2026-10-24
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1842)
Duration: 1:59, non-stop
Airbus A321 (321)
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This flight number is listed as serving the following routes:
  • Cancun (CUN) - Atlanta (ATL)
  • Detroit (DTW) - Minneapolis/Saint Paul (MSP)
  • Omaha (OMA) - Atlanta (ATL)
All KLM flights
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