Delta Air Lines flight DL 5381: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Thu,Fri,Sun 14:07 Detroit (DTW) M 15:07 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-01-23 through 2026-01-29
Thu,Fri,Sun 14:07 Detroit (DTW) M 15:07 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-02-01 through 2026-02-06
Mon 14:07 Detroit (DTW) M 15:07 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Operates only on 2026-02-09
Mon,Thu 14:09 Detroit (DTW) M 15:09 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-01-19 through 2026-01-26
Mon,Fri 14:09 Detroit (DTW) M 15:09 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-01-30 through 2026-02-02
Daily 14:15 Detroit (DTW) M 15:10 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 0:55 Effective 2026-04-13 through 2026-10-05
Daily 14:15 Detroit (DTW) M 15:09 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 0:54 Effective from 2026-10-06
Sun 15:30 Detroit (DTW) M 16:32 Cleveland (CLE)
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:02 Operates only on 2026-02-08
Sat 17:10 Columbia (CAE) 18:21 Atlanta (ATL) S
DL 5381 Non-stop Canadair CRJ 900 (CR9) 1:11 Effective 2026-03-14 through 2026-04-11
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This flight number is listed as serving the following routes:


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Delta Air Lines flight DL 5381: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Delta Air Lines DL5381
14:07
Detroit (DTW) M

15:07
Cleveland (CLE)
Effective 2026-01-23 through 2026-01-29
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:07
Detroit (DTW) M

15:07
Cleveland (CLE)
Effective 2026-02-01 through 2026-02-06
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:07
Detroit (DTW) M

15:07
Cleveland (CLE)
Operates only on 2026-02-09
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:09
Detroit (DTW) M

15:09
Cleveland (CLE)
Effective 2026-01-19 through 2026-01-26
Mon
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:09
Detroit (DTW) M

15:09
Cleveland (CLE)
Effective 2026-01-30 through 2026-02-02
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:15
Detroit (DTW) M

15:10
Cleveland (CLE)
Effective 2026-04-13 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:55, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
14:15
Detroit (DTW) M

15:09
Cleveland (CLE)
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:54, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
15:30
Detroit (DTW) M

16:32
Cleveland (CLE)
Operates only on 2026-02-08
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:02, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5381
17:10
Columbia (CAE)

18:21
Atlanta (ATL) S
Effective 2026-03-14 through 2026-04-11
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:11, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Columbia (CAE) - Atlanta (ATL)
  • Detroit (DTW) - Cleveland (CLE)
All Delta Air Lines flights
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