American Airlines flight AA 5222: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Mon-Sat 08:00 Chicago O'Hare (ORD) 3 10:43 Knoxville (TYS)
AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-12 through 2026-03-07
Sun 08:00 Chicago O'Hare (ORD) 3 10:43 Knoxville (TYS)
AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-22 through 2026-03-01
Mon,Wed-Sun 08:00 Chicago O'Hare (ORD) 3 10:45 Knoxville (TYS)
AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-03-08 through 2026-04-06
Tue 08:05 Chicago O'Hare (ORD) 3 10:50 Knoxville (TYS)
AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-03-10 through 2026-03-31
Daily 08:45 Dallas Fort Worth (DFW) 12:04 Dayton (DAY)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 2:19 Effective 2026-01-06 through 2026-02-11
Sun 11:13 Knoxville (TYS) 12:16 Chicago O'Hare (ORD) 3
AA 5222 Non-stop Canadair CRJ 700 (CR7) 2:03 Effective 2026-02-22 through 2026-03-01
Daily 13:00 Charlotte (CLT) 14:08 Charleston (CHS)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:08 Effective 2026-08-05 through 2026-09-08
Daily 13:05 Charlotte (CLT) 14:25 Charleston (CHS)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:20 Effective 2026-09-09 through 2026-10-04
Sun 13:10 Chicago O'Hare (ORD) 3 15:52 Knoxville (TYS)
AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:42 Operates only on 2026-02-15
Daily 14:35 Charlotte (CLT) 16:01 Washington Dulles (IAD)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:26 Effective 2026-05-21 through 2026-07-01
Daily 14:35 Charlotte (CLT) 16:00 Washington Dulles (IAD)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:25 Effective 2026-07-02 through 2026-08-04
Daily 14:38 Charleston (CHS) 15:52 Charlotte (CLT)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:14 Effective 2026-08-05 through 2026-09-08
Daily 15:15 Charleston (CHS) 16:34 Charlotte (CLT)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:19 Effective 2026-09-09 through 2026-10-04
Daily 17:39 Washington Dulles (IAD) 19:40 Charlotte (CLT)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 2:01 Effective 2026-07-02 through 2026-08-04
Daily 17:47 Washington Dulles (IAD) 19:40 Charlotte (CLT)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:53 Effective 2026-05-21 through 2026-07-01
Daily 18:14 Dayton (DAY) 20:00 Dallas Fort Worth (DFW)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 2:46 Effective 2026-04-07 through 2026-05-20
Mon,Tue,Thu-Sun 21:58 Charlotte (CLT) 23:43 Wilkes-Barre/Scranton (AVP)
AA 5222 Non-stop Canadair CRJ 900 (CR9) 1:45 Valid until 2026-01-05
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This flight number is listed as serving the following routes:
American Airlines flight AA 5222: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA5222
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-02-22 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-02-22 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:08, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:20, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Operates only on 2026-02-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

American Airlines AA5222
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:25, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:14, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:19, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:01, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:46, non-stop
Canadair CRJ 900 (CR9)

Direct Flights:

American Airlines AA5222
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Charlotte (CLT) - Charleston (CHS)
  • Charlotte (CLT) - Washington Dulles (IAD)
  • Charlotte (CLT) - Wilkes-Barre/Scranton (AVP)
  • Dayton (DAY) - Dallas Fort Worth (DFW)
  • Knoxville (TYS) - Chicago O'Hare (ORD)