American Airlines flight AA 4649: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 07:30 Nashville (BNA) 10:06 Raleigh/Durham (RDU) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-09-09 through 2026-10-04
Mon-Sat 13:10 New York LaGuardia (LGA) B 14:39 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:29 Effective 2026-04-07 through 2026-05-20
Daily 13:40 Philadelphia (PHL) 15:14 Raleigh/Durham (RDU) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:34 Effective 2026-03-08 through 2026-04-06
Daily 13:50 Philadelphia (PHL) 15:26 Raleigh/Durham (RDU) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-02-12 through 2026-03-07
Daily 14:58 Ronald Reagan Washington (DCA) 2 16:34 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2026-08-05 through 2026-09-08
Mon-Fri,Sun 15:34 Boston Logan (BOS) B 17:51 Chicago O'Hare (ORD) 3
AA 4649 Non-stop Embraer EMB 175 (E75) 3:17 Valid until 2026-01-05
Sat 15:42 Boston Logan (BOS) B 17:59 Chicago O'Hare (ORD) 3
AA 4649 Non-stop Embraer EMB 175 (E75) 3:17 Valid until 2026-01-03
Daily 17:14 Nantucket (ACK) 19:00 Ronald Reagan Washington (DCA) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2026-08-05 through 2026-09-08
Daily 19:10 New York LaGuardia (LGA) B 21:21 Columbia (CAE)
AA 4649 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:11 Effective from 2026-10-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4649: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4649
07:30
Nashville (BNA)

10:06
Raleigh/Durham (RDU) 2
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
13:10
New York LaGuardia (LGA) B

14:39
Pittsburgh (PIT)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 1:29, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
13:40
Philadelphia (PHL)

15:14
Raleigh/Durham (RDU) 2
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
13:50
Philadelphia (PHL)

15:26
Raleigh/Durham (RDU) 2
Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
14:58
Ronald Reagan Washington (DCA) 2

16:34
Nantucket (ACK)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
15:34
Boston Logan (BOS) B

17:51
Chicago O'Hare (ORD) 3
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 3:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
15:42
Boston Logan (BOS) B

17:59
Chicago O'Hare (ORD) 3
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 3:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
17:14
Nantucket (ACK)

19:00
Ronald Reagan Washington (DCA) 2
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4649
19:10
New York LaGuardia (LGA) B

21:21
Columbia (CAE)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:11, non-stop
Embraer EMB 170 / EMB 175 (E70)
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - Chicago O'Hare (ORD)
  • Nashville (BNA) - Raleigh/Durham (RDU)
  • New York LaGuardia (LGA) - Columbia (CAE)
  • New York LaGuardia (LGA) - Pittsburgh (PIT)
  • Philadelphia (PHL) - Raleigh/Durham (RDU)
  • Ronald Reagan Washington (DCA) - Nantucket (ACK)
All American Airlines flights
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