American Airlines flight AA 4389: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 07:00 Boston Logan (BOS) B 09:29 John Glenn Columbus (CMH)
AA 4389 Non-stop Embraer EMB 175 (E75) 2:29 Effective from 2026-10-05
Daily 08:30 Ronald Reagan Washington (DCA) 2 11:45 Key West (EYW)
AA 4389 Non-stop Embraer EMB 175 (E75) 3:15 Effective 2026-08-05 through 2026-09-08
Mon-Fri,Sun 09:00 Boston Logan (BOS) B 11:33 John Glenn Columbus (CMH)
AA 4389 Non-stop Embraer EMB 175 (E75) 2:33 Effective 2026-01-07 through 2026-02-11
Daily 12:00 John Glenn Columbus (CMH) 13:58 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 1:58 Effective from 2026-10-05
Daily 12:03 John Glenn Columbus (CMH) 14:02 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2026-01-06 through 2026-02-11
Daily 12:18 Key West (EYW) 15:08 Ronald Reagan Washington (DCA) 2
AA 4389 Non-stop Embraer EMB 175 (E75) 2:50 Effective 2026-08-05 through 2026-09-08
Mon-Thu 12:29 John Glenn Columbus (CMH) 14:34 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2026-02-16 through 2026-02-26
Mon-Fri 12:29 John Glenn Columbus (CMH) 14:34 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2026-02-27 through 2026-03-06
Sun 12:35 John Glenn Columbus (CMH) 14:41 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:06 Effective 2026-02-15 through 2026-03-01
Thu 12:37 John Glenn Columbus (CMH) 14:43 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:06 Operates only on 2026-02-12
Fri 12:44 John Glenn Columbus (CMH) 14:50 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:06 Effective 2026-02-13 through 2026-02-20
Mon-Fri,Sun 12:45 John Glenn Columbus (CMH) 14:45 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2026-03-08 through 2026-04-06
Sat 13:04 John Glenn Columbus (CMH) 15:10 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:06 Effective 2026-02-14 through 2026-03-07
Sat 13:05 John Glenn Columbus (CMH) 15:05 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2026-03-14 through 2026-04-04
Daily 14:59 New York John F. Kennedy (JFK) 8 16:51 Cleveland (CLE)
AA 4389 Non-stop Embraer EMB 175 (E75) 1:52 Effective 2026-05-21 through 2026-07-01
Mon,Tue,Thu,Fri,Sun 15:55 New York LaGuardia (LGA) B 17:18 Ronald Reagan Washington (DCA) 2
AA 4389 Non-stop Embraer EMB 175 (E75) 1:23 Valid until 2026-01-05
Sat 15:57 New York LaGuardia (LGA) B 17:20 Ronald Reagan Washington (DCA) 2
AA 4389 Non-stop Embraer EMB 175 (E75) 1:23 Valid until 2026-01-03
Daily 16:40 Chicago O'Hare (ORD) 3 17:49 Cedar Rapids (CID)
AA 4389 Non-stop Embraer EMB 175 (E75) 1:09 Effective 2026-04-07 through 2026-05-20
Daily 17:22 Cleveland (CLE) 19:10 New York John F. Kennedy (JFK) 8
AA 4389 Non-stop Embraer EMB 175 (E75) 1:48 Effective 2026-05-21 through 2026-07-01
Daily 18:31 Cedar Rapids (CID) 19:50 Chicago O'Hare (ORD) 3
AA 4389 Non-stop Embraer EMB 175 (E75) 1:19 Effective 2026-04-07 through 2026-05-20
Daily 18:45 New York LaGuardia (LGA) B 20:56 Charleston (CHS)
AA 4389 Non-stop Embraer EMB 175 (E75) 2:11 Effective 2026-09-09 through 2026-10-04
Daily 22:00 New York John F. Kennedy (JFK) 8 23:34 Boston Logan (BOS) B
AA 4389 Non-stop Embraer EMB 175 (E75) 1:34 Effective 2026-07-02 through 2026-08-04
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4389: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4389
07:00
Boston Logan (BOS) B

09:29
John Glenn Columbus (CMH)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
08:30
Ronald Reagan Washington (DCA) 2

11:45
Key West (EYW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:15, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
09:00
Boston Logan (BOS) B

11:33
John Glenn Columbus (CMH)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:33, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:00
John Glenn Columbus (CMH)

13:58
Boston Logan (BOS) B
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:03
John Glenn Columbus (CMH)

14:02
Boston Logan (BOS) B
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:18
Key West (EYW)

15:08
Ronald Reagan Washington (DCA) 2
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:50, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:29
John Glenn Columbus (CMH)

14:34
Boston Logan (BOS) B
Effective 2026-02-16 through 2026-02-26
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:29
John Glenn Columbus (CMH)

14:34
Boston Logan (BOS) B
Effective 2026-02-27 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:35
John Glenn Columbus (CMH)

14:41
Boston Logan (BOS) B
Effective 2026-02-15 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:06, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:37
John Glenn Columbus (CMH)

14:43
Boston Logan (BOS) B
Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:06, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:44
John Glenn Columbus (CMH)

14:50
Boston Logan (BOS) B
Effective 2026-02-13 through 2026-02-20
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:06, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
12:45
John Glenn Columbus (CMH)

14:45
Boston Logan (BOS) B
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
13:04
John Glenn Columbus (CMH)

15:10
Boston Logan (BOS) B
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:06, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
13:05
John Glenn Columbus (CMH)

15:05
Boston Logan (BOS) B
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
14:59
New York John F. Kennedy (JFK) 8

16:51
Cleveland (CLE)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:52, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
15:55
New York LaGuardia (LGA) B

17:18
Ronald Reagan Washington (DCA) 2
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:23, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
15:57
New York LaGuardia (LGA) B

17:20
Ronald Reagan Washington (DCA) 2
Valid until 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:23, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
16:40
Chicago O'Hare (ORD) 3

17:49
Cedar Rapids (CID)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:09, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
17:22
Cleveland (CLE)

19:10
New York John F. Kennedy (JFK) 8
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
18:31
Cedar Rapids (CID)

19:50
Chicago O'Hare (ORD) 3
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:19, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
18:45
New York LaGuardia (LGA) B

20:56
Charleston (CHS)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:11, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4389
22:00
New York John F. Kennedy (JFK) 8

23:34
Boston Logan (BOS) B
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Cedar Rapids (CID)
  • Cleveland (CLE) - New York John F. Kennedy (JFK)
  • John Glenn Columbus (CMH) - Boston Logan (BOS)
  • Key West (EYW) - Ronald Reagan Washington (DCA)
  • New York John F. Kennedy (JFK) - Boston Logan (BOS)
  • New York LaGuardia (LGA) - Charleston (CHS)
  • New York LaGuardia (LGA) - Ronald Reagan Washington (DCA)
All American Airlines flights
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