American Airlines flight AA 4280: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 09:40 Chicago O'Hare (ORD) 3 11:20 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:40 Effective 2026-09-09 through 2026-10-04
Daily 13:31 Chicago O'Hare (ORD) 3 16:48 Providence (PVD)
AA 4280 Non-stop Embraer EMB 175 (E75) 2:17 Valid until 2026-01-05
Daily 13:59 Dallas Fort Worth (DFW) 15:27 New Orleans (MSY)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:28 Effective 2026-08-05 through 2026-09-08
Daily 14:26 Kansas City (MCI) 16:10 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2026-09-09 through 2026-10-04
Daily 16:11 New Orleans (MSY) 17:54 Dallas Fort Worth (DFW)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2026-08-05 through 2026-09-08
Sat 17:12 Dallas Fort Worth (DFW) 18:50 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:38 Effective 2026-02-14 through 2026-03-07
Daily 17:25 Providence (PVD) 19:35 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 3:10 Valid until 2026-01-05
Tue 17:32 Miami (MIA) 19:25 Charleston (CHS)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:53 Effective 2026-02-17 through 2026-03-03
Tue 20:10 Charleston (CHS) 21:53 Miami (MIA)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2026-02-17 through 2026-03-03
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This flight number is listed as serving the following routes:
American Airlines flight AA 4280: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA4280
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:28, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:38, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-02-17 through 2026-03-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:53, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4280
Effective 2026-02-17 through 2026-03-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Charleston (CHS) - Miami (MIA)
  • Dallas Fort Worth (DFW) - Kansas City (MCI)
  • Kansas City (MCI) - Chicago O'Hare (ORD)
  • New Orleans (MSY) - Dallas Fort Worth (DFW)
  • Providence (PVD) - Chicago O'Hare (ORD)