Alaska Airlines flight AS 6452: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 05:11 Knoxville (TYS) 06:10 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 4536)
Daily 05:17 Knoxville (TYS) 06:10 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:53 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 3918)
Daily 05:33 John Glenn Columbus (CMH) 06:05 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Airbus A319 (319) 1:32 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 1193)
Mon-Fri,Sun 14:44 Chicago O'Hare (ORD) 3 17:13 Louisville (SDF)
AS 6452 Non-stop Embraer EMB 175 (E75) 1:29 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 4432)
Daily 14:50 Chicago O'Hare (ORD) 3 17:14 Louisville (SDF)
AS 6452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:24 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 3796)
Mon,Thu,Fri,Sun 15:14 Chicago O'Hare (ORD) 3 17:40 Louisville (SDF)
AS 6452 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-02-12 through 2026-03-06
Codeshare flight, operated by American Airlines.(AA 4432)
Daily 16:19 Dallas Fort Worth (DFW) 17:49 Memphis (MEM)
AS 6452 Non-stop Embraer EMB 175 (E75) 1:30 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 3527)
Daily 17:04 Knoxville (TYS) 18:00 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5168)
Mon-Fri,Sun 18:12 Louisville (SDF) 19:00 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Embraer EMB 175 (E75) 1:48 Effective 2026-03-08 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 4432)
Mon,Thu,Fri,Sun 18:16 Louisville (SDF) 19:12 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2026-02-12 through 2026-03-06
Codeshare flight, operated by American Airlines.(AA 4432)
Daily 18:20 Memphis (MEM) 20:00 Dallas Fort Worth (DFW)
AS 6452 Non-stop Embraer EMB 175 (E75) 1:40 Effective 2026-08-05 through 2026-09-08
Codeshare flight, operated by American Airlines.(AA 3527)
Daily 19:15 Louisville (SDF) 19:50 Chicago O'Hare (ORD) 3
AS 6452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:35 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 3796)
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This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 6452: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS6452
05:11
Knoxville (TYS)

06:10
Chicago O'Hare (ORD) 3
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4536)
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
05:17
Knoxville (TYS)

06:10
Chicago O'Hare (ORD) 3
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3918)
Duration: 1:53, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Codeshare Flights:
Alaska Airlines AS6452
05:33
John Glenn Columbus (CMH)

06:05
Chicago O'Hare (ORD) 3
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1193)
Duration: 1:32, non-stop
Airbus A319 (319)
Direct Codeshare Flights:
Alaska Airlines AS6452
14:44
Chicago O'Hare (ORD) 3

17:13
Louisville (SDF)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 1:29, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
14:50
Chicago O'Hare (ORD) 3

17:14
Louisville (SDF)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3796)
Duration: 1:24, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Codeshare Flights:
Alaska Airlines AS6452
15:14
Chicago O'Hare (ORD) 3

17:40
Louisville (SDF)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
16:19
Dallas Fort Worth (DFW)

17:49
Memphis (MEM)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3527)
Duration: 1:30, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
17:04
Knoxville (TYS)

18:00
Chicago O'Hare (ORD) 3
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5168)
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)
Direct Codeshare Flights:
Alaska Airlines AS6452
18:12
Louisville (SDF)

19:00
Chicago O'Hare (ORD) 3
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 1:48, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
18:16
Louisville (SDF)

19:12
Chicago O'Hare (ORD) 3
Effective 2026-02-12 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 4432)
Duration: 1:56, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
18:20
Memphis (MEM)

20:00
Dallas Fort Worth (DFW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3527)
Duration: 1:40, non-stop
Embraer EMB 175 (E75)
Direct Codeshare Flights:
Alaska Airlines AS6452
19:15
Louisville (SDF)

19:50
Chicago O'Hare (ORD) 3
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3796)
Duration: 1:35, non-stop
Embraer EMB 170 / EMB 175 (E70)
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This flight number is listed as serving the following routes:
  • Dallas Fort Worth (DFW) - Memphis (MEM)
  • John Glenn Columbus (CMH) - Chicago O'Hare (ORD)
  • Knoxville (TYS) - Chicago O'Hare (ORD)
  • Louisville (SDF) - Chicago O'Hare (ORD)
All Alaska Airlines flights
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